Preheat oven to 375°. Prepare a baking dish with nonstick pan spray. Sprinkle salt and pepper over both sides of tilapia fillets; set aside. Combine artichokes, breadcrumbs, Parmesan cheese, and oregano in a medium bowl; mix well. Brush each fillet with 1/2 teaspoon olive oil; top with the parmesan mixture. Bake until fish pulls apart easily with a fork (about 15 minutes).
Sprinkle each serving with chopped fresh parsley just before serving. Serve it with steamed broccoli or rice.